<正>In the present time, coronavirus disease COVID-19 has become prevalent across the globe and declared as a pandemic by the world health organization(WHO) . As of now, many vaccines and medicines are in the approval process or at different stages of preclinical investigations to coup with the COVID-19 . Coronavirus has a spike protein, which tends to bind with receptors present in the lung tissues, and that helps in its entry to the cells and replication inside . Therefore, we are in need to design the multivalent nanomaterials, which can act as receptors to bind with spike protein of virus and stop its replication(Fig. 1).