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Mechanism of Helicobacter pylori-induced apoptosis in human gastric epithelial cells

Sang Hui CHU;Hyeyoung KIM;Kyung Hwan KIM

   Helicobacter pylori (H.pylori) has been shown to be an important pathogen of a wide variety of diseases including duodenal ulceration,gastritis,gastric adenocarcinoma,and gastric B-cell lymphoma.But thorough investigations into H.pylori-induced apoptosis and subsequent molecular mechanisms are not well defined.One of the potential toxic factors involving H.pylori-induced gastric injury is oxygen radicals that are released from activated neutrophils,because……