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Interventional therapy of malignant obstructive jaundice


   OBJECTIVE: To assess the short-term results of interventional therapy for malignant obstructivejaundice.METHODS: In 82 patients with malignant obstructive jaundice, hepatocellular carcinoma was detected in10 patients, carcinoma of gallbladder in 14, hilar biliary carcinoma in 22, pancreatic carcinoma in 20,and hilar metastatic carcinoma in 16. Percutaneous transhepatic biliary internal and/or external drainage(PTBIED) was performed in 61 patients and percutaneous transhepatic insertion of biliary stent (PTIBS)in 21.RESULTS: The level of total serum bilirubin (TSB) was reduced in 71 patients and less markedly inothers. The level of TSB of the 61 patients was redueed from 450.12±113.51 μmol/L before operation to240.25±107.81 μmol/L and 90.91±101.72 μmol/L1 and 2 weeks after operation respectively. TheTSB level of the 21 patients was reduced from 410.53±98.13 μmol/L to 270.23±115.64 μmol/L and105.43±97.85 μmol/L 1 and 2 weeks after operation, respectively. No significant difference was foundin the effect between PTBIED and PTIBS. Short-term complications developed in 33 patients. Sevenpatients died 30 days after operation.CONCLUSION: Interventional therapy may be simple, safe and effective in the treatment of malignantobstructive jaundice.……