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戊唑醇对映体在新型纤维素键合手性固定相上的拆分

明永飞;赵亮;张红丽;师彦平;李永民

  The chiral stationary pahse of 3,5-dimethylphenylcarbamates of cellulose chemically bonded to 3-aminopropyl silica gel at the 6-position of the glucose units was prepared.The racemates of tebuconazole were resolved on the new immobilized chiral stationary phase,and the influences of modifiers(alcohols,THF and chloroform) in the mobile phase on the resolution were investigated.The chromatographic conditions were optimized.The results show that the new immobilized chiral stationary phase exhibits a good stereoselectivity to tebuconzole.The best resolution of 1.51 of tebuconazole was obtained by using hexane/2-propanol/ THF(volume ratio 90∶5∶5) as the mobile phase on a 150 mm column.……   
[关键词]:键合;手性固定相;手性拆分;戊唑醇
[文献类型]:期刊
[文献出处]: 《高等学校化学学报2007年02期
[格式]:PDF原版; EPUB自适应版(需下载客户端)