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Study on Fluorescence Property of Sparfloxacin Derivatizing System and its Application


  In acid medium, sparfloxacin is oxidized by nitrous acid. then reacts with hydrobromic acid to form a new fluorescence substance. which can emit the strong fluorescence. which is 151 fold more than that of sparfloxacin itself. By this . a new sensitive method for the determination of sparfloxacin in human urine by derivative-synchronous fluorescence is presented with good results.……